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Diamond-based materials for biomedical applicationsEdited by R Narayan, University of North Carolina, USA
Woodhead Publishing Series in Biomaterials No. 55
- presents the fundamental principles and novel applications of this versatile material
- discusses the functionalization of diamond particles and surfaces, biotribology and biological behaviour of nanocrystalinediamond coatings and blood compatibility of diamond-like carbon coatings
- reviews nanostructured diamond coatings for orthopaedic coatings
- explores ultrananocrystaline diamond for neural and opthalmological applications, nanodiamonds for drug delivery systems and diamond nucleation and seeding techniques for tissue regeneration
Carbon is light weight, strong, conductive and able to mimic natural materials within the body, making it ideal for many uses within biomedicine. Consequently a great deal of research and funding is being put into this interesting material with a view to increasing the variety of medical applications for which it is suitable. Diamond-based materials for biomedical applications presents readers with the fundamental principles and novel applications of this versatile material.
Part one provides a clear introduction to diamond based materials for medical applications. Functionalization of diamond particles and surfaces is discussed, followed by biotribology and biological behaviour of nanocrystalline diamond coatings, and blood compatibility of diamond-like carbon coatings. Part two then goes on to review biomedical applications of diamond based materials, beginning with nanostructured diamond coatings for orthopaedic applications. Topics explored include ultrananocrystalline diamond for neural and ophthalmological applications, nanodiamonds for drug delivery systems, and diamond nucleation and seeding techniques for tissue regeneration. Finally, the book concludes with a discussion of diamond materials for microfluidic devices.
With its distinguished editors and international team of expert contributors, Diamond-based materials for biomedical applications is an authoritative guide for all materials scientists, researchers, medical practitioners and academics investigating the properties and uses of diamond based materials in the biomedical environment.
ISBN 0 85709 340 1
ISBN-13: 978 0 85709 340 0
March 2013
296 pages 234 x 156mm hardback
£130.00 / US$220.00 / €155.00
Usually dispatched within 24 hours
About the editor
Roger Narayan is Professor in the Joint Department of Biomedical Engineering at the University of North Carolina-Chapel Hill and North Carolina State University. The author of over one hundred publications as well as several book chapters on nanoscale and microscale processing, characterization, and modeling of biological and biomedical materials, Dr Narayan also serves as an editorial board member for several academic journals.
Titles which may also be of interest:
Coatings for biomedical applications
Bioactive materials in medicine
Contents
PART 1 INTRODUCTION TO DIAMOND BASED MATERIALS FOR MEDICAL APPLICATIONS
PART 2 BIOMEDICAL APPLICATIONS OF DIAMOND BASED MATERIALS
PART 1 INTRODUCTION TO DIAMOND BASED MATERIALS FOR MEDICAL APPLICATIONS
Introduction to medical applications of diamond particles and surfaces
R J Narayan and R D Boehm, University of North Carolina and North Carolina State University, USA and A V Sumant, Argonne National Laboratory, USA
- Introduction
- Growth of synthetic diamond
- Diamond-based medical devices
- Functionalization of nanodiamond and nanocrystalline diamond
- Drug delivery using nanodiamond
- Imaging with nanodiamond
- Conclusion
- Acknowledgments
- References
Functionalisation of diamond surfaces for medical applications
S Szunerits and R Boukherroub, Université Lille, France
- Introduction
- Electrochemical reduction of aryldiazonium salts
- Photochemical modification
- Preparation of amine-terminated diamond surfaces
- Preparation of oxygen-terminated diamond surfaces
- Conclusion and future trends
- References
Biotribology and biological behaviour of nanocrystalline diamond (NCD) coatings for medical applications
M Amaral, University of Aveiro, Portugal
- Introduction to nanocrystalline diamond (CVD)
- NCD coated silicon nitride ceramics as new materials for joint replacement
- Growth and characterization of NCD films deposited on SiNsubstrates
- Biotribology of NCD coatings
- Biological behaviour of NCD coated SiNceramics
- References
Blood compatibility of diamond-like carbon (DLC) coatings
M Fedel, University of Trento, Italy
- Introduction
- Diamond-like carbon (DLC) structure, properties and applications
- Deposition techniques for DLC films
- DLC blood compatibility
- Modified DLC films
- Biomedical applications of DLC coatings
- Conclusion and future trends
- References
PART 2 BIOMEDICAL APPLICATIONS OF DIAMOND BASED MATERIALS
Nanostructured diamond coatings for orthopaedic applications
S A Catledge, V Thomas and Y K Vohra, University of Alabama at Birmingham, USA
- Introduction
- Ultra-hard carbon coatings
- Wear measurements for ceramic-based orthopaedic implants
- Mesenchymal stem cells derived from bone marrow and their interactions with nanostructured diamond surfaces
- Macrophage cells interactions to diamond wear debris
- In vivo evaluation of nanostructured diamond surfaces
- Future trends - Acknowledgements
- References
Ultrananocrystalline diamond (UNCD) films for ophthalmological applications
O Auciello and P Gurman, Argonne National Laboratory, USA, A Berra, Universidad Nacional de Buenos Aires, Argentina, M Saravia, Hospital Austral, Argentina, R Zysler, Centro Atómico Bariloche, Argentina
- Introduction
- The use of ultrananocrystalline diamond (UNCD) films as coatings in the restoration of sight in people blinded by degenerated photoreceptors
- The use of UNCD films in the treatment of glaucoma
- Integrated magnet/superparamagnetic nanoparticles interacting system for new treatment of retina detachment
- Conclusions
- Acknowledgments
- References
Ultrananocrystalline diamond (UNCD) for neural applications
Y-C Chen, National Hsinchu University of Education, Taiwan and Harvard Medical School, USA, D-C Lee, Institute of Cellular and System Medicine, Taiwan, N-H Tai, National Tsing-Hua University, Taiwan, I-M Chiu, Institute of Cellular and System Medicine, Taiwan, National Chung Hsing University, Taiwan and The Ohio State University, USA
- Introduction
- Mechanism aspects of ultrananocrystalline diamond (UNCD)/neural cell interactions
- Methods of guiding neurons
- Neural and retinal prostheses
- References
Nanodiamonds for drug delivery systems
A E Mengesha, Drake University, USA and B-B C Youan, University of Missouri-Kansas City, USA
- Introduction
- Surface modification of diamond nanoparticles for drug delivery and targeting
- Development of nanodiamond-based drug delivery for proteins
- Development of nanodiamond-based drug delivery for genes
- Development of nanodiamond-based drug delivery for low molecular weight therapeutic agents
- Biocompatibility, biodistribution and biological fate of nanodiamonds
- Conclusions
- References
Diamond nucleation and seeding techniques for tissue regeneration
A Kromka, O Babchenko, S Potocky, B Rezek, A Sveshnikov, P Demo, T Izak and M Varga, Academy of Sciences of the Czech Republic, Czech Republic and Slovak University of Technology in Bratislava, Slovak Republic
- Introduction
- Diamond nucleation
- Methods for diamond nucleation and seeding
- Bias enhanced nucleation in hot filament chemical vapour deposition (HF CVD)
- Ultrasonic seeding
- Seeding using a polymer composite
- Spontaneous nucleation
- Biological and tissue engineering applications
- Acknowledgement
- References
Diamond materials for microfluidic devices
A Karczemska, Lodz University of Technology, Poland
- Introduction
- Materials for the manufacture of microfluidic devices
- Diamond microfluidic devices
- Conclusions and future trends
- Acknowledgments
- References