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This item is in: Food Science > Functional foods and nutrition

Jacket image for Food and cancer prevention – Woodhead Publishing
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Food and cancer prevention: Chemical and biological aspects

K W Waldron, I T Johnson and G R Fenwick, Institute of Food Research, UK

Woodhead Publishing Series in Food Science, Technology and Nutrition No. 14

Food and cancer prevention: Chemical and biological aspects is the first book to be published on this subject and represents the current state-of-the-art. It is interdisciplinary in scope and provides researchers from around the world with the opportunity to bring themselves up-to-date in this vital area.

Food and cancer prevention: Chemical and biological aspects covers a topic which is attracting considerable attention and aims to promote constructive collaboration among clinicians, toxicologists, nutritionists, food scientists, epidemiologists and plant scientists worldwide. It is an essential reading for anyone involved in research in to this subject and will also be of interest to government departments, with a view to legislation, and food manufacturers producing functional, novel or health foods.

ISBN 1 85573 781 7
ISBN-13: 978 1 85573 781 5
January 1993
462 pages  234 x 156mm  hardback  
£180.00 / US$305.00 / €215.00
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Titles which may also be of interest:
Functional foods, ageing and degenerative disease
Functional foods, cardiovascular disease and diabetes
Phytochemical functional foods
Food diet and obesity


Contents

Part 1 The Relationships between Diet and Cancer in Human Populations
PART 2 THE OCCURRENCE AND SIGNIFICANCE OF CARCINOGENS IN FOODS
PART 3 FREE RADICAL REACTIONS AND ANTIOXIDANT NUTRIENTS IN THE ETIOLOGY OF HUMAN CANCERS
PART 4 TUMOUR INITIATION: THE SIGNIFICANCE OF ENDOGENOUS BIOTRANSFORMATION ENZYMES AND THEIR MODULATION BY DIET
PART 5 SUPPRESSING TUMOUR DEVELOPMENT: THE ROLE OF DIET IN THE MODULATION OF CELL PROLIFERATION
PART 6 IMMUNE MECHANISM: THE ROLE OF FOOD COMPONENTS AS IMMUNOREGULATORS
PART 7 DIETARY FIBRE AND RELATED SUBSTANCES
PART 8 RESEARCH TECHNIQUE: NEW APPROACHES
PART 9 IMPLICATIONS FOR PUBLIC HEALTH

Part 1 The Relationships between Diet and Cancer in Human Populations

Food: Its Role in the Etiology of Cancer
Gary M. Williams

Inhibition of Carcinogenesis by Nonnutrient Constituents of the Diet
Lee W. Wattenberg

Polychlorinated Dibenzo-p-dioxins, Polychlorinated Dibenzofurans, and the Food Chain
James R. Startin

Contribution of Epidemiology in Elucidating the Role of Foods In Cancer Prevention
D. Kromhout, H.B. Bueno de Mesquita and M.G.L. Hertog

Diet and Mammographc Patterns: Work in Progress
Timothy Key, David Forman, Louise Cotton, Ann Lewis, Gwyneth Davey, John Moore, Graham Clark, Christine Mlynek, Joyce Tarrant, Philip Savage, Ruth English and Basil Shepstone

Workshop Report: New Developments in Epidemiology
W.P.T. James

PART 2 THE OCCURRENCE AND SIGNIFICANCE OF CARCINOGENS IN FOODS

Genotoxic Effects of Nitrosamines and Cooked Food Mutagens in Various Organs of Mice and Their Modification by Dietary Factors
S. Knasmüller, W. Parzefall, W. Huber, H. Kienzl and R. Schulte-Hermann

Influence of Sugar-Linked- and Diallyl-Dithiocarbamates on Mutagenic and Carcinogenic N-Nitroso Compounds
B. H. Lee, B. Bertram, P. Schmezer and M. Wiesler

In vitro Genetic Toxicology Testing of Naturally Occurring Isothiocyanates
S. R. R. Musk and I. T. Johnson

Possible Clastogenic and Anticlastogenic Actions of Fermented Milk “Narine”
A. K. Nersessian

Influence of Dietary Fat on Metabolism of 2-Amino-3-Methyl-3H-IMIDAZO[4,5-f]Quinoline (IQ)
C.J. Rumney, I.R. Rowland and I.K. O'Neill

Influence of Diet on the Conversion of 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-f]Quinoline (IQ) to the 7-Keto Derivative (7-OHIQ)
C.J. Rumney and I.R. Rowland

Antimutagenic Action of Beta Carotene, Canthaxanthin and Extracts of Rosmarinus Officinalis and Melissa Officinalis. Genotoxicity of Basil and Tarragon Oil
Amalia Bianchi-Santamaria, Fernando Tateo and Leonida Santamaria

Nitrite-Free Meat Curing Systems and the N-Nitrosamine Problem
F. Shahidi and R.B. Pegg

Carbohydrates, Especially Mono- and Disaccharides in Excess Inhibit the Formation of Mutagenic Heterocyclic Amines During Frying of Meat
K. I. Skog and I. M. Jägerstad

Effects of Ellagic Acid, Tannic Acid and Quercetin on the Mutagenic Activity of Cooked Food Mutagens in the Salmonella Strain TA98
Michael Strube, Preben Aagaard Nielsen and John C. Larsen

Analysis of Human Sera for Aflatoxin
A.P. Wilkinson, D.W. Denning, H.A. Lee, C.M. Ward and M.R.A. Morgan

Workshop Report: Dietary Carcinogenesis - What Role in Human Cancer?
W. Jongen

PART 3 FREE RADICAL REACTIONS AND ANTIOXIDANT NUTRIENTS IN THE ETIOLOGY OF HUMAN CANCERS

Chemical Aspects and Biological Mechanisms of Anticancer Nutrients in Plant Foods
D. I. Thurnham

Antioxidant and Pro-Oxidant Actions of Dietary Components
O.I. Aruoma and B. Halliwell

In Vitro Antioxidant Activity of Lutein
M. Chopra and D. I. Thurnham

Effect of Vitamin A Dietary Intake on DNA Damage Induced in vitro by AFB1
S. Decoudu, P. Cassand, V. Colin, B. Koch and J.F. Narbonne

Availability of Soluble All-Trans Versus 9-CIS β-Carotene
G. Levin and S. Mokady

Effects of Dietary Anticarcinogens on Rat Hepatic and Intestinal Glutathione S-Transferases
W.A. Nijhoff and W.H.M. Peters

Quantitation of Provitamin-A and Non-Provitamin-A Carotenoids in the Fruits Most Commonly Consumed in Spain
B. Olmedilla, F. Granado, I. Blanco and E. Rojas-Hidalgo

Seasonal Variation of Serum Levels of β-Carotene and α-Tocopherol
M. Rautalahti, D. Albanes, J. Haukka, E. Roos and J. Virtamo

Antioxidant Vitamins or Lactulose as Chemopreventive Agents for Colorectal Cancer
L. Roncucci and M. Ponz de Leon

Carotenoids Plus Vitamin a in Cancer Prevention, Adjuvant Therapy, and Mastalgia Treatment (*)
Leonida Santamaria and Amalia Bianchi-Santamaria

Workshop Report: Role of Anti-Oxidants in Cancer Protection
D.G. Lindsay

PART 4 TUMOUR INITIATION: THE SIGNIFICANCE OF ENDOGENOUS BIOTRANSFORMATION ENZYMES AND THEIR MODULATION BY DIET

Modulation of Biotransformation Enzymes by Non-Nutritive Dietary Factors
Peter J. van Bladeren

Effect of Cooking and of Vegetables and Fruit On 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats
G. M. Alink, H. A. Kuiper, V. M. H. Hollanders and J. H. Koeman

Studies of Antimutagenic Factors in Food
G. Bronzetti, E. Morichetti, C. Salvadori and C. Della Croce

Does the Type of Fat Influence Intestinal and Hepatic Microsomal Metabolism?
R. Chinery, R. A. Goodlad, N. A. Wright and J. T. Borlak

Chemical and Biochemical Basis for Beneficial Effects of Sulfhydryl Compounds on Food Safety
Mendel Friedman

Determination of Potentially Anticarcinogenic Flavonoids in Foods and Preliminary Results on Daily Intake in the Netherlands
M.G.L. Hertog, P.C.H. Hollman and D. Kromhout

The Content of the Potentially Anticarcinogenic Ellagic Acid in Plant Foods
C.H. Peter Hollman and P. Dini Venema

Inhibitory Effect of an Extract of Leaves of Rosmarinus Officinalis L. on Tumor Initiation and Promotion in the Skin of CD-1 Mice
M-T. Huang, C-T. Ho, Z. Y. Wang, K. Stauber, C. Georgiadis, J.D. Laskin and A.H. Conney

Vitamin a as A Modulator of In vitro Unschedulded DNA Synthesis Induced by 2-AMINO-3-Methylimidazo[4,5-]Quinoline and 2-AMINO-3,4-Dimethylimidazo[4,5-]Quinoline in Rat Hepatocyte Primary Cultures
B. KOCH, S. BLOWERS, I. ROWLAND and J.F. NARBONNE

Comparison of Hydroxylated and Non-Hydroxylated Natural Flavonoids as In vitro Modulators of Rat Hepatic Benzo(a)Pyrene Metabolism
A.M. Le Bon, L. Ziegler and M. Suschetet

The Distribution of Quercetin and Quercetin Glycosides in Vegetable Components of The Human Diet
Terrance Leighton, Charles Ginther and Larry Fluss

In Vivo Studies on Antigenotoxic Effects of Na-Phytate and L. Casei in the Gastrointestinal Tract of Rats
B.L. Pool-Zobel, B. Bertram, K.D. Jany, U. Schlemmer and W.H. Holzapfel

Desmutagenic Effect of Vegetables on Mutagens and Carcinogens and Growth-inhibiting Effect of Spinach Components on Cultured Human Cancer Cells
K. Shinohara, M. Kobori and Z-L. Kong

Potential Anti-Mutagenicity and Anti-Carcinogenicity of Some Plant Phenols
R. Walker, A.D. Ayrton and C. Ioannides

Inhibition of Nitrosamine-Induced Tumorigenesis by Diallyl Sulfide and Tea
C. S. Yang, J-Y. Hong and Z.-Y. Wang

PART 5 SUPPRESSING TUMOUR DEVELOPMENT: THE ROLE OF DIET IN THE MODULATION OF CELL PROLIFERATION

Role of Dietary Factors in the Modulation of Cancer Induction
M. B. ROBERFROID

Diet and Breast Cancer
H Leon Bradlow, Nitin T Telang, Jon J Michnovicz and Michael P Osborne

Proliferative Activity in the Colon of Healthy Subjects in Two Italian Cities With Different Dietary Habits
Giovanna Caderni, Franca Bianchini and M.Teresa Spagnesi

Effects of Short Chain Fatty Acid Infusion on the Gastrointestinal Epithelium of Intravenously Fed Rats
RA Goodlad, R Chinery, CY Lee, MA Ghatei, SR Bloom and NA Wright

In vitro Studies Into the Selective Toxicity of Allyl Isothiocyanate Towards Transformed Human Tumour Cells
S. R. R. Musk and I. T. Johnson

Cancer Preventive Agents in Processed Garlic
Hoyoku Nishino

Omega 3 Fatty Acids Suppress Mucosal Crypt Cell Production in Rats
J.D. Pell, J.C. Brown and I.T. Johnson

Workshop Report: Increased Cell Proliferation as A Cause of Human Cancer
R. Goodlad

Workshop Report: Dietary Protective Factors - New Candidates
L. Wattenburg

PART 6 IMMUNE MECHANISM: THE ROLE OF FOOD COMPONENTS AS IMMUNOREGULATORS

Bioactive Cell Wall and Related Components From Herbal Products and Edible Plant Organs as Protective Factors
K. W. Waldron and R. R. Selvendran

Anti-Tumorigenic and Immunoactive Protein and Peptide Factors in Foodstuffs (I) - Anti-Tumorigenic Protein From Tricholoma Matsutake -
Y. Kawamura and M. Ishikawa

Anti-Tumorigenic and Immunoactive Protein and Peptide Factors in Foodstuffs (II)- Anti-Tumorigenic Factors in Rice Bran -
Y. Kawamura and M. Muramoto

PART 7 DIETARY FIBRE AND RELATED SUBSTANCES

Plant Cell Wall Material and Cancer Protection
S. A. Bingham

Lignans and Isoflavonoids of Dietary Origin and Hormone-Dependent Cancer
H. Adlercreutz, M. Carson, Y. Mousavi, A. Palotie, S. Booms, M. Loukovaara, T. Mäkelä, K. Wähälä, G. Brunow and T. Hase

Bile Acids in a Human Model of Colorectal Neoplasia
DM Bradburn, IR Rowland, JC Mathers, A Gunn, J Burn and IDA Johnston

Variations of Colonic Proliferation, Cecal and Fecal pH in Rats Fed Different Carbohydrates
Giovanna Caderni, Cristina Luceri and M. Teresa Spagnesi

Insoluble Dietary Fibre Rich Fractions From Barley Protect Rats From Intestinal Cancers
G.H. McIntosh, L. Jorgensen and P. Royle

Dietary Fibre and the Gastrointestinal Epithelium: Differential Response in the Stomach, Small Intestine and Colon of Conventional and Germ-Free Rats
B Ratcliffe, CY Lee, NA Wright and RA Goodlad

Influence of Dietary Fibers on Two Intestinal Transferases in Rats Inoculated With A Whole Human Faecal Flora
N. ROLAND, L. NUGON-BAUDON and O. SZYLIT

Nitrite-Binding Properties of Dietary Fibres
F. Shahidi and C. Hong

Workshop Report: Non-Starch Polysaccharides (NSP) and Colorectal Cancer: The Current Position
S. Bingham

PART 8 RESEARCH TECHNIQUE: NEW APPROACHES

Toxicological Methods to Study Mechanisms of Naturally Occurring Anticarcinogens
Wim.M.F. Jongen

Isolation and Identification of Putative Carcinogens and Anticarcinogens From Dietary and Faecal Samples by Supercritical Fluid Extraction and HPLC
A. D'Odorico, I.T. Gilmore, A. Morris, A.J. Young and R.F. Bilton

Cell Proliferation and Morphometry in Endoscopic Biopsies
RA Goodlad, S Levi, CY Lee and NA Wright

Detection of Abnormal Mucosal Cell Replication in Humans: A Simple Technique
J.A. Matthew, J.D. Pell, A. Prior, H.J. Kennedy, I.W. Fellows, J.M. Gee and I.T. Johnson

Rapid Detection of Inducers of Enzymes That Protect Against Carcinogens
Hans J. Prochaska, Annette B. Santamaria and Paul Talalay

Isolation and Identification of the Principal Inducer of Anticarcinogenic Protective Enzymes From Broccoli
Y. Zhang, P. Talalay, C.-G. Cho and G.H. Posner

Quantitation of Isothiocyanates by Cyclocondensation With 1, 2-Benzenedithiol
Y. Zhang, C.-G. Cho, G.H. Posner and P. Talalay

The Biological Assay of Natural Mutagens Using the P53 Gene
C. E. Couet, A. B. Hanley, S. Macdonald and L. Mayes

Workshop Report: Research Techniques - In Vivo Methodologies
Okezie I. Aruoma

Workshop Report: In Vitro Methodology
G. Williamson

PART 9 IMPLICATIONS FOR PUBLIC HEALTH

Implications for Dietary Guidance
W. P. T. James

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