This item is in: Food Science > Safety > Pathogens and mycotoxins

Detection methods for cynobacterial toxins

Edited by G A Codd, University of Dundee, T M Jefferies, University of Bath, C W Keevil, Centre for Applied Microbiology and Research and E Potter, National Rivers Authority, UK

Cyanobacteria, or blue-green algae, commonly occur in a variety of water types throughout the world. A variable, but, high proportion of the cyanobacterial blooms and scums, which can develop annually in lakes, reservoirs, canals and slow-flowing rivers, contain potent toxins. Although animal poisonings and human health problems associated with the ingestion of, or contact with, cyanobacterial scums have long been recognized, a developing understanding of the health hazards posed by the toxins requires that reliable, sensitive, specific and convenient methods are available for their detection and quantification.

Detection methods for cynobacterial toxins looks at the application of biological, toxicological, biochemical and physicochemical techniques in studies of cyanobacterial toxins and at experimental methods that have identified at least 50 cyanobacterial compounds toxic to vertebrates.

Academics, public health bodies, environmental protection agencies and water companies are all involved in monitoring cyanobacterial levels and effects, and this book will help to ensure that their research is not duplicated, is standardized and comparable, and that optimal progress can be made in an important area that is still in its developing stages.

ISBN 1 85573 802 3
ISBN-13: 978 1 85573 802 7
January 1994
202 pages  242 x 169mm  hardback  
£145.00 / US$245.00 / €175.00

Usually dispatched within 24 hours

An e-book version of this title is available to purchase as part of a Collection or Pick n Mix or by Chapter. Visit Woodhead Publishing Online

Titles which may also be of interest:
Microbiological risk assessment in food processing
Mycotoxins in food

Contents

Health problems from exposure to cyanobacteria and proposed safety guidelines for drinking and recreational water
I R Falconer

An epidemiological critique of reports of human illness associated with cyanohacteria
P R Hunter

Cyclic peptide hepatotoxins from fresh water cyanobacteria water blooms collected in the river dnieper reservoirs and other water bodies from the European part of Russia
V M Tchernajenko

Structural analysis of cyanobacterial toxins
K-iHarada, M Suzuki and M F Watanabe

Determinations of anatoxin-a, homoanatoxin and propylanatoxin in cyanobacterial extracts by HPLC, GC-mass spectrometry and capillary electrophoresis
T M Jefferies, G Brainmer, A Zotou, P A Brough and T Gallagher

Enantiomer-specific analysis of homoanatoxin-a. a cyanophyte neurotoxin
J-E Haugen, M Oehme and M D Muller

Neurotoxins from Australian Anabaena
D A Steffensen. A R Humpage, J Rositano, A H Bretag, R Brown, P D Baker and B C Nicholson

The analysis of microcystin-LR in water: application in water
H A James, C P James and J Hart

The analysis of microcystins in raw and treated water
L A Lawton, C Edwards and G A Codd

Application of HPLC and mass spectrometry (MALDI) to the detection and identification of toxins from microcystis, oscillatoria and aphanizomenon from several freshwater reservoirs
C S Dow, U K Swoboda, P Firth and N Smith

Routes of intoxication
R B Firzgeorge, S A Clark and C W Keevil

Testing of toxicity in cyanobacteria by cellular assay
I E Erilcsson, D M Toivota, M Reinikainen. C M L Rábergh and J A 0 Meriluoto

A sensitive bioscreen for detection of cyclic peptide toxins of the microcystin class
C F B Holmes, T L McCreadv, M Craig, T W Lambert and S E Hrudev

The inhibition of protein phosphatases by toxins: implications for health and an extremely sensitive and rapid bioassay for toxin detection
C MacKintosh and R W MacKintosh

Detection of hepatotoxins by protein phosphatase inhibition assay: advantages, pitfalls and anomalies
A T R Sim and L-M Mudge

Alternatives to the mouse bioassay for cyanobacterial toxicity assessment
U K Swoboda, C S Dow, J Chaivimol, N Smith and B P Pound

Evaluation of assay methods for the determination of cyanobacterial hepatotoxicity
L A Lawton, K A Beattie, S P Hawser, D L Campbell and G A Codd

The role of synthetic chemistry in the production of standards for toxin analysis
T Gallagher, P A Brough, T M Jefferies and S Wonnacoti

Sources of uncertainty in assessing the health risk of cyanobacterial blooms in drinking water supplies
S E Hrudey, S L Kenefick, T W Lambert, B G Korak, E E Prepas and C F B Holmes

Standing committee of analysts
D Westwood

Toxic cyanobacteria (blue-green algae) in Portuguese freshwaters
V Vasconcelos

Screening of cyanobactenal toxins in microcystis aeruginosa collected from blooms and cultures
F van Hoof, T van Es, D. D’hont and N de Pauw

Toxicity studies with blue-green algae from Flemish reservoirs
F van Hoof, P Castelain, M Kirsch- Vokiers and J Vankerkom

Cases of cyanobacterial toxicoses on Swiss alpine pastures
K Mez, H-R Preisig, B Winkenbach, K Hanselmann, R Bachofen, B Hauser and H Nageli

Biological and economic significance of benthic cyanobacteria in two Scottish highland lochs
K P Owen

First results on the occurrence of microcystin-LR in Berlin and Brandenburg lakes
J Fastner

Variation of cyanobacterial hepatotoxins in Finland
K Sivonen, M Nainikoshi, R Luukkainen, M.Fardig, L Rouhialnen, W R Evans. W W Carmichael, K L Rinehart and S I Niemelä

A method for the detection of cyanobacterial peptide toxins by HPLC
J Rositano and B C Nicholson

Release and degradation of microcystin during a microcystis aeru bloom in a freshwater reservoir
C S Dow, U K Swoboda and P Firth

Characterization of hepatotoxins from freshwater oscillatoria species: variation in toxicity and temporal expression
J Chaivimol, U K Swoboda and C S Dow

Expression of cyanotoxins in environmental biomass containing species of oscillatoria
U K Swoboda and C S Dow

A simple and rapid method for extraction of toxic peptides from cyanobacteria
N Gjolme and H Utkilen

Phosphatase assay as a determinant of hepatotoxin toxicity
I Claivimol, U K Swoboda and C S Dow

Detection of cyanobacterial (blue-green algal) peptide toxins by protein phosphatase inhibition
C Edwards, L A Lawton and G A Codd

Investigation of the solution conformation of microcystins-LR and -RR by high field nuclear magnetic resonance
B Mulloy and R Wait

The tandem mass spectrometry of nodularin, microcystins and other cyclic peptides
V C M Dale, D Despeyroux and K R Jennings