This item is in: Materials > Biomaterials > Applications
Nanomedicine: Technologies and applicationsEdited by T J Webster, Brown University, USA
Woodhead Publishing Series in Biomaterials No. 49
- provides an important review of nanomedicine technology and its growing range of applications
- discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings
- reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering
- later chapters focus on cartilage and bone tissue engineering, regeneration and replacement
Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications.
After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement.
With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field.
ISBN 0 85709 233 2
ISBN-13: 978 0 85709 233 5
October 2012
704 pages 234 x 156mm hardback
£175.00 / US$300.00 / €210.00
Usually dispatched within 24 hours
About the editor
Dr Thomas J. Webster is Director of the Nanomedicine Laboratory and Associate Professor in the Schools of Engineering and Orthopedic Surgery at Brown University, USA. The founding editor-in-chief of the International Journal of Nanomedicine, Professor Webster is also on the editorial board of 10 other journals, has organized over 25 symposia at academic conferences, and has won multiple awards for his research.
Titles which may also be of interest:
Drug-device combination products
Biomedical composites
Surface modification of biomaterials
Nanomaterials in tissue engineering
Contents
PART 1 MATERIALS, PROPERTIES AND CONSIDERATIONS
PART 2 NANOMEDICINE FOR THERAPEUTICS AND IMAGING
PART 3 NANOMEDICINE FOR SOFT TISSUE ENGINEERING
PART 4 NANOMEDICINE FOR BONE AND CARTILAGE TISSUE ENGINEERING
PART 1 MATERIALS, PROPERTIES AND CONSIDERATIONS
Introduction to nanomedicine
C Yao, Nanovis LLC and J Lu, Purdue University, USA
- Introduction: basic concepts of nanomedicine
- Public perception of nanomedicine
- Scientific principles and applications of nanomedicine
- Future trends in nanomedicine
- References
Trends in nanomedicine
F Allhoff, Western Michigan University, USA and The Australian National University, Australia
- Introduction
- The rise of nanomedicine
- Diagnostics and medical records
- Treatment
- Future trends
- References
Biomedical nanocrystalline metals and alloys: structure, properties and applications
D Facchini, Integran Technologies, Inc, Canada
- Introduction
- Synthesis and structure of nanocrystalline metals and alloys
- Properties of nanocrystalline metals and alloys
- Biocompatibility of nanocrystalline metals and alloys
- Applications of nanocrystalline metals and alloys
- Future trends
- Sources of further information and advice
- References
Nanoporous gold for biomedical applications: structure, properties and applications
T M Martin, University of North Carolina Chapel Hill and North Carolina State University, D B Robinson, Sandia National Laboratories and R J Narayan, University of North Carolina Chapel Hill and North Carolina State University, USA
- Introduction
- Medical applications
- Gold nanoporous biosensors
- Alloy formation
- Dealloying of gold silver alloy
- Mechanical properties of nanoporous gold
- Electronic properties of nanoporous gold
- Conclusions
- References
Hydroxyapatite (HA) coatings for biomaterials
P Choudhury and DC Agrawal, CSJM University, India
- Introduction
- Hydroxyapatite (HA) coatings
- HA coatings by plasma spraying
- Properties of plasma sprayed caotings
- Biomimetic HA coatings
- HA coatings by sol-gel deposition
- Deposition techniques for HA coatings
- Conclusions
- Future trends
- Acknowledgement
- References
PART 2 NANOMEDICINE FOR THERAPEUTICS AND IMAGING
Calcium-phosphate coated magnetic nanoparticles for treating bone diseases
R A Pareta, Institute for Regenerative Medicine, USA and S Sirivisoot, King Mongkut's University of Technology Thonburi, Thailand
- Introduction
- Iron oxide magnetic nanoparticle synthesis
- Surface modification of iron oxide magnetic nanoparticles
- Characterization of iron oxide magnetic nanoparticles
- Biological applications of magnetic nanoparticles
- Conclusions
- Future trends
- References
Orthopaedic carbon nanotube biosensors for controlled drug delivery
S Sirivisoot, King Mongkut's University of Technology Thonburi, Thailand and R A Pareta, Wake Forest Institute for Regenerative Medicine, USA
- Introduction
- Carbon nanotubes for electrochemical biosensing
- Carbon nanotube-based in situ orthopedic implant sensors
- Electrically controlled drug delivery systems for infection and inflammation
- Critical issues in developing in situ orthopedic implantable sensors and devices
- Conclusions
- References
Nanostructured selenium anti-cancer coatings for orthopaedic applications
P A Tran and T J Webster, Brown University, USA
- Introduction
- Selenium as an anti-cancer implant material
- Nano-structured selenium coatings: A novel approach of using selenium to create anti-cancer biomaterials
- In vitro biological assays for uncoated and selenium coated metallic substrates
- The effectiveness of titanium and stainless steel substrates
- Coarse - grained Monte Carlo computer simulation of fibronectin adsorption on nanometer rough surfaces
- Conclusions
- References
Nanoparticulate targeted drug delivery using peptides and proteins
H A Santos and L M Bimbo, University of Helsinki, Finland, J das Neves, University of Porto, Portugal; B Sarmento, University of Porto and Instituto Superior de Ciências da Saúde – Norte, Portugal
- Introduction
- Peptides and proteins for targeted drug delivery
- Drug-peptide conjugates
- Peptide-functionalized drug delivery systems
- Peptide-targeted drug delivery across the intestine
- Peptide-targeted drug delivery across the blood-brain barrier (BBB)
- Peptide-targeted drug delivery for cancer applications
- Peptide-targeted drug delivery for the liver
- Conclusions and future trends
- References
Nanotechnology for DNA and RNA delivery
H Yu, Boston College, USA; Y Chen, Brown University, USA
- Introduction on DNA and RNA delivery
- Advanced DNA/RNA delivery approaches in nanotechnology
- Nanomaterial applications for DNA/RNA delivery
- Novel vaccines
- Molecular probes and images
- Conclusions and future trends
- References
Gold nanoshells for imaging and photothermal ablation of cancer
A J Coughlin and J L West, Rice University, USA
- Introduction
- The impact of cancer
- Cancer biology
- Nanotechnology and cancer treatment
- Nanoshells
- Conclusions and future trends
- Sources of further information and advice
- Acknowledgements
- References
Microfluidics for testing and delivering nanomedicine
H van Heeren, enablingMNT -the Netherlands, The Netherlands
- Introduction
- Microfluidics
- Testing of nanomedicine with microfluidic instruments
- Delivery of nanomedicine using microfluidic technology
- Nanoparticles
- Conclusions and future trends
- References
Zinc oxide nanowires for biomedical sensing and analysis
M Willander and O Nur, Linköping University, Sweden
- Introduction
- Electrode growth and preparation
- Sensors and functionalization
- Measurement and results
- Conclusions
- References
PART 3 NANOMEDICINE FOR SOFT TISSUE ENGINEERING
Nanotechnology and tissue engineered organ regeneration
A O Oseni and A M Seifalian, University College London, UK
- Introduction
- Nanotechnology and tissue engineering
- Nanotechnology and organ regeneration
- Future trends and challenges
- References
Rapid fabrication of biomimetic nanofiber-enabled skin grafts
H Wang and X Fu, Stevens Institute of Technology, USA
- Introduction
- Autologous skin tissue engineering for wound healing
- The effects of microenvironment on the formation of skin substitute
- Production of biomimetic nanofibers using electrostatic spinning
- Layer-by-layer assembly of cells into 3D construct using electrospun nanofibers
- Rapid formation of skin grafts using the nanofiber-enabled cell layering approach
- Future trends and challenges
- Conclusion
- Acknowledgement
- References
Nanotubes for tissue engineering
P E Mikael, University of Connecticut, J A Wallace, University of Connecticut Health Center and S P Nukavarapu, University of Connecticut, USA
- Introduction
- Nanotubes for tissue engineering
- Nanotube applications in tissue engineering
- Nanotubes and their effects
- Conclusions
- References
Self-assembled nanomaterials for tissue engineering applications
A Alsbaiee, R L Beingessner and H Fenniri, University of Alberta, Canada
- Introduction
- Peptide-based self-assembled nanomaterials
- Applications of peptide-based materials in tissue engineering
- Nucleic acid based nanomaterials
- Applications of rosette nanotubes in bone and cartilage tissue engineering
- References
PART 4 NANOMEDICINE FOR BONE AND CARTILAGE TISSUE ENGINEERING
Electrically active biocomposites for smart scaffolds for bone tissue engineering
A K Dubey and K Balani, IIT Kanpur, B Basu, Indian Institute of Science, India
- Introduction
- Composition and electrical properties of natural bone
- Effect of external E-field on cells
- Development of HA- based bone replacement materials
- Conclusions
- Acknowledgement
- References
Nanotechnology for cartilage and bone regeneration
L G Zhang, J Li and J D Lee, The George Washington University, USA
- Introduction
- Cartilage repair and regeneratio n
- Bone repair and regeneration
- Future trends and conclusions
- References
Nanostructured materials for bone tissue replacement
M Musib and S Saha, SUNY Downstate Medical Center, USA
- Introduction
- The need for nano-engineered bone
- Surface properties of orthopedic materials
- Nano coating on conventional surfaces
- Nanomaterials for orthopedic tissue engineering
- Future trends and ethical concerns
- Conclusions
- References
Nanocomposites for cartilage regeneration
J Lock and H Liu, University of California, Riverside, USA
- Introduction
- Design criteria and considerations for cartilage biomaterials
- Biomaterials for cartilage regeneration
- Scaffold fabrication
- Conclusions and future trends
- References