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Minimized cardiopulmonary bypass techniques and technologiesEdited by T Gourlay, University of Strathclyde, UK and S Gunaydin, K. Kale University, Turkey
Woodhead Publishing Series in Biomaterials No. 40
The book is comprehensive in its scope and authoritative in the experience of its chapter authors. I commend the book to all members of cardiac surgery teams - surgeons, cardiologists, anaesthetists and perfusionists.
Professor Ken Taylor, Emeritus Professor of Cardiac Surgery, Imperial College and The Hammersmith Hospital, London (from the Foreword)
- covers a broad range of cardiopulmonary bypass (CPB) pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces and optimal haemodilution levels
- focuses on new equipment specially developed for minimized-CPB and myocardial protection protocols
- discusses clinical issues, including patient selection
- an invaluable reference for cardiac surgery teams and academics researching this important area
Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative bleeding. Minimised cardiopulmonary bypass techniques use developments in perfusion technology to significantly reduce foreign surface-blood interactions to make bypass simpler and safer. This important book reviews key developments and issues relating to this promising technology.
Part one covers the broad range of CPB pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces, optimal haemodilution levels, and the important issue of CPB-induced systemic inflammatory response syndrome. Part two focuses on the issues of the new equipment developed for mini-CPB, optimal myocardial protection protocols and CPB perfusate options. Part three discusses clinical issues, including patient selection, coronary and valve surgery protocols and, among others, paediatric patients.
With its distinguished editors and international team of expert contributors, Minimized cardiopulmonary bypass techniques and technologies is a valuable reference for cardiac surgery teams and those researching this important technology.
ISBN 1 84569 800 2
ISBN-13: 978 1 84569 800 3
April 2012
272 pages 234 x 156mm hardback
£130.00 / US$220.00 / €155.00
Usually dispatched within 24 hours
About the editors
Terence Gourlay is Professor of Medical Diagnostics in the Department of Biomedical Engineering at University of Strathclyde, UK.
Serdar Gunaydin is Professor in the Department of Cardiovascular Surgery, K. Kale University, Turkey. Both are internationally-renowned for their research in innovative CPB techniques.
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Contents
PART 1 INTRODUCTION TO MINIMIZED CARDIOPULMONARY BYPASS
PART 1 INTRODUCTION TO MINIMIZED CARDIOPULMONARY BYPASS
PART 2 MINIMIZED CARDIOPULMONARY BYPASS EQUIPMENT
PART 2 MINIMIZED CARDIOPULMONARY BYPASS EQUIPMENT
PART 3 CLINICAL APPLICATIONS OF MINIMIZED CARDIOPULMONARY BYPASSES
PART 3 CLINICAL APPLICATIONS OF MINIMIZED CARDIOPULMONARY BYPASSES
PART 1 INTRODUCTION TO MINIMIZED CARDIOPULMONARY BYPASS
PART 1 INTRODUCTION TO MINIMIZED CARDIOPULMONARY BYPASS
Historical development of minimized cardiopulmonary bypass
T Gourlay, University of Strathclyde, UK and S Gunaydin, University of Kirikkale, Turkey
- Introduction and historical perspective
- Cardiopulmonary bypass from pioneering to refinement
- Cardiopulmonary bypass – does size matter?
- Conclusions
- References
Historical development of minimized cardiopulmonary bypass
T Gourlay, University of Strathclyde, UK and S Gunaydin, University of Kirikkale, Turkey
- Introduction and historical perspective
- Cardiopulmonary bypass from pioneering to refinement
- Cardiopulmonary bypass – does size matter?
- Conclusions
- References
Anticoagulation protocols for minimized cardiopulmonary bypass
M Ranucci, IRCCS Policlinico SDonato, Italy
- Introduction: blood activation during cardiac surgery with cardiopulmonary bypass (CPB)
- Anticoagulation during CPB: basic principles and historical notes
- Heparin-bonded surfaces and other biocompatible treatments
- Reduction of systemic heparinization (RSH)
- Cautions
- Future trends
- References
Anticoagulation protocols for minimized cardiopulmonary bypass
M Ranucci, IRCCS Policlinico SDonato, Italy
- Introduction: blood activation during cardiac surgery with cardiopulmonary bypass (CPB)
- Anticoagulation during CPB: basic principles and historical notes
- Heparin-bonded surfaces and other biocompatible treatments
- Reduction of systemic heparinization (RSH)
- Cautions
- Future trends
- References
Minimized extracorporeal circulation: physiology and pathophysiology
I Dimarakis, V Joshi and W Hesford, Wythenshawe Hospital, G Asimakopoulos, Bristol Heart Institute, UK
- Introduction: basic principles
- The inflammatory cascade and biomarkers
- Conclusions
- References
Minimized extracorporeal circulation: physiology and pathophysiology
I Dimarakis, V Joshi and W Hesford, Wythenshawe Hospital, G Asimakopoulos, Bristol Heart Institute, UK
- Introduction: basic principles
- The inflammatory cascade and biomarkers
- Conclusions
- References
Blood–surface interface in miniatururised extracorporeal circulation systems
T Gourlay and L Shedden, University of Strathclyde, UK
- Introduction
- Blood-surface contact in cardiopulmonary bypass (CPB)
- Clinical benefits of miniaturised extracorporeal circulation systems
- References
Blood–surface interface in miniatururised extracorporeal circulation systems
T Gourlay and L Shedden, University of Strathclyde, UK
- Introduction
- Blood-surface contact in cardiopulmonary bypass (CPB)
- Clinical benefits of miniaturised extracorporeal circulation systems
- References
Hemodilution: physiology and pathophysiology
J Wegner, Midwestern University, USA
- Introduction
- Basic physiology and pathophysiology of hemodilution
- Microvascular alterations with hemodilution
- Hemodilution and cardiopulmonary bypass (CPB)
- Determinants of tissue oxygenation - functional capillary density (FCD)
- Conclusions
- References
Hemodilution: physiology and pathophysiology
J Wegner, Midwestern University, USA
- Introduction
- Basic physiology and pathophysiology of hemodilution
- Microvascular alterations with hemodilution
- Hemodilution and cardiopulmonary bypass (CPB)
- Determinants of tissue oxygenation - functional capillary density (FCD)
- Conclusions
- References
Inflammatory response and minimized cardiopulmonary bypass
A H Olivencia-Yurvati and R T Mallet, University of North Texas Health Science Center, USA
- Introduction
- Cardiopulmonary bypass (CPB)-induced inflammatory cascade
- Pharmacological antioxidants for CPB: impact on biochemical and clinical outcomes
- Miniaturized CPB circuits
- Conclusions
- Acknowledgements
- References
- Appendix: abbreviations
Inflammatory response and minimized cardiopulmonary bypass
A H Olivencia-Yurvati and R T Mallet, University of North Texas Health Science Center, USA
- Introduction
- Cardiopulmonary bypass (CPB)-induced inflammatory cascade
- Pharmacological antioxidants for CPB: impact on biochemical and clinical outcomes
- Miniaturized CPB circuits
- Conclusions
- Acknowledgements
- References
- Appendix: abbreviations
PART 2 MINIMIZED CARDIOPULMONARY BYPASS EQUIPMENT
PART 2 MINIMIZED CARDIOPULMONARY BYPASS EQUIPMENT
Design and principles of the minimized extracorporeal circuit
H I Ucar, A C Yorgancioglu, Medicana International Hospital, S Gunaydin, University of Kirikkale, Turkey
- Introduction
- Basic principles of minimized extracorporeal circulation
- Evolution of minimized circuits
- Minimized extracorporeal systems available in the market
- Surgical applications of minimized extracorporeal circulation
- Controversies and challenges facing minimized cardiopulmonary bypass
- Future trends in minimized cardiopulmonary bypass
- References
Design and principles of the minimized extracorporeal circuit
H I Ucar, A C Yorgancioglu, Medicana International Hospital, S Gunaydin, University of Kirikkale, Turkey
- Introduction
- Basic principles of minimized extracorporeal circulation
- Evolution of minimized circuits
- Minimized extracorporeal systems available in the market
- Surgical applications of minimized extracorporeal circulation
- Controversies and challenges facing minimized cardiopulmonary bypass
- Future trends in minimized cardiopulmonary bypass
- References
Cardiopulmonary bypass perfusate
D Phiroz, Rapides Regional Medical Center, USA
- Introduction
- Crystalloid primes
- Types of crystalloids and colloid agents used in prime
- Pharmacological agents used in prime
- Using prime in CPB procedures
- Examples of prime combinations
- Minimizing the use of prime
- Conclusions
- References
Cardiopulmonary bypass perfusate
D Phiroz, Rapides Regional Medical Center, USA
- Introduction
- Crystalloid primes
- Types of crystalloids and colloid agents used in prime
- Pharmacological agents used in prime
- Using prime in CPB procedures
- Examples of prime combinations
- Minimizing the use of prime
- Conclusions
- References
Myocardial preservation techniques for mini-bypass
P Punjabi and M Zakkar, Hammersmith Hospital, UK
- Introduction
- Methods of myocardial protection: Myocardial protection in mini bypass
- Conclusion
- References
Myocardial preservation techniques for mini-bypass
P Punjabi and M Zakkar, Hammersmith Hospital, UK
- Introduction
- Methods of myocardial protection: Myocardial protection in mini bypass
- Conclusion
- References
PART 3 CLINICAL APPLICATIONS OF MINIMIZED CARDIOPULMONARY BYPASSES
PART 3 CLINICAL APPLICATIONS OF MINIMIZED CARDIOPULMONARY BYPASSES
Minimized cardiopulmonary bypass: objectives and indications
A El-Essawi and W Harringer, Klinikum Braunschweig, Germany
- Introduction: objectives of minimised cardiopulmonary bypass
- Indications and patient selection
- Future trends
- References
Minimized cardiopulmonary bypass: objectives and indications
A El-Essawi and W Harringer, Klinikum Braunschweig, Germany
- Introduction: objectives of minimised cardiopulmonary bypass
- Indications and patient selection
- Future trends
- References
Coronary artery bypass grafting (CABG)
J Skorpil, Pilsen Medical Center, Czech Republic
- Introduction
- History of coronary artery bypass grafting (CABG)
- Patient selection (indications) for miniinvazive cardiopulmonary bypass
- Conduits
- Anastomoses techniques
- Surgical management of miniinvazive cardiopulmonary bypass
- Conclusions
- References
Coronary artery bypass grafting (CABG)
J Skorpil, Pilsen Medical Center, Czech Republic
- Introduction
- History of coronary artery bypass grafting (CABG)
- Patient selection (indications) for miniinvazive cardiopulmonary bypass
- Conduits
- Anastomoses techniques
- Surgical management of miniinvazive cardiopulmonary bypass
- Conclusions
- References
Valve surgery using minimized perfusion circuits
I Kutschka and H Baraki, Hannover Medical University, Germany
- Introduction
- Surgical and technical aspects
- Blood management and patient treatment in valve surgery
- Experience with closed loop perfusion circuits in valve surgery
- References
Valve surgery using minimized perfusion circuits
I Kutschka and H Baraki, Hannover Medical University, Germany
- Introduction
- Surgical and technical aspects
- Blood management and patient treatment in valve surgery
- Experience with closed loop perfusion circuits in valve surgery
- References
Minimising cardiopulmonary bypass in children
M H D Danton and I Torrance, Royal Hospital for Sick Children, UK
- Introduction
- Challenges of cardiopulmonary bypass (CPB) in the congenital patient
- Potential goals of Mini-CPB
- Mini-CPB and neurological outcome
- Mini-CPB circuit design options in congenital heart surgery
- Clinical trials
- Alternative procedures to CPB
- Conclusions
- References
- Appendix: abbreviations
Minimising cardiopulmonary bypass in children
M H D Danton and I Torrance, Royal Hospital for Sick Children, UK
- Introduction
- Challenges of cardiopulmonary bypass (CPB) in the congenital patient
- Potential goals of Mini-CPB
- Mini-CPB and neurological outcome
- Mini-CPB circuit design options in congenital heart surgery
- Clinical trials
- Alternative procedures to CPB
- Conclusions
- References
- Appendix: abbreviations
Comparison of minimized circulation with off-pump coronary artery bypass grafting (OPCAB) and conventional surgery
U Demirkilic, GATA Medical School, E Sener, Ataturk Training and Research Hospital and S Gunaydin, University of Kirikkale, Turkey
- Introduction
- Controversies and challenges facing off pump coronary artery bypass grafting (OPCAB)
- Studies comparing OPCAB versus mini-cardiopulmonary bypass (CPB) and mini-CPB assisted OPCAB
- Future trends and competition between OPCAB and minimized cardiopulmonary bypass
- References
Comparison of minimized circulation with off-pump coronary artery bypass grafting (OPCAB) and conventional surgery
U Demirkilic, GATA Medical School, E Sener, Ataturk Training and Research Hospital and S Gunaydin, University of Kirikkale, Turkey
- Introduction
- Controversies and challenges facing off pump coronary artery bypass grafting (OPCAB)
- Studies comparing OPCAB versus mini-cardiopulmonary bypass (CPB) and mini-CPB assisted OPCAB
- Future trends and competition between OPCAB and minimized cardiopulmonary bypass
- References
Minimally invasive cardiac surgery, port-access and robotic surgery
T Modine, Clinique de Chirurgie Cardiovasculaire Hopital Cardiologique de Lille, France
- Introduction
- Minimally invasive coronary artery bypass grafting
- Minimally invasive valve surgery
- Minimally invasive congenital surgery
- Minimally invasive treatment of atrial fibrillation
- Miscellaneous possibilities of minimally invasive surgery
- Robotic surgery
- Conclusion
- References
Minimally invasive cardiac surgery, port-access and robotic surgery
T Modine, Clinique de Chirurgie Cardiovasculaire Hopital Cardiologique de Lille, France
- Introduction
- Minimally invasive coronary artery bypass grafting
- Minimally invasive valve surgery
- Minimally invasive congenital surgery
- Minimally invasive treatment of atrial fibrillation
- Miscellaneous possibilities of minimally invasive surgery
- Robotic surgery
- Conclusion
- References