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Metabolomics in food and nutritionEdited by B C Weimer and C M Slupsky, University of California, Davis, USA
Woodhead Publishing Series in Food Science, Technology and Nutrition No. 251
- provides an overview of the current and potential future use of metabolomics in the food industry
- chapters focus on key applications and review the analytical methods used and the bioinformatics techniques involved in processing the results
Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality. Metabolomics analysis of human biofluids will also help to determine the relationship between diet and health. This book provides an overview of the current and potential use of metabolomics in the food industry. Opening chapters review the analytical methods used and the bioinformatics techniques involved in processing the results. Further chapters focus on key applications.
ISBN 1 84569 512 7
ISBN-13: 978 1 84569 512 5
October 2013
256 pages 234 x 156mm hardback
Approx. £120.00 / US$205.00 / €145.00
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Contents
PART 1 EQUIPMENT, METHODS AND DATA INTERPRETATION IN METABOLOMICS
PART 2 APPLICATIONS OF METABOLOMICS IN HUMANS, PLANTS AND FOOD
PART 1 EQUIPMENT, METHODS AND DATA INTERPRETATION IN METABOLOMICS
Equipment and metabolite identification (ID) strategies for mass-based metabolomic analysis
C J Wachsmuth, P J Oefner and K Dettmer, University of Regensburg, Germany
- Introduction
- Liquid chromatography
- Gas chromatography
- Mass spectrometry technologies
- Analytical systems
- Compound identification (ID) approaches
- Databases for tracking and interconnections
- Future trends
- Sources of further information and advice
- Acknowledgements
- References
Metabolomics using nuclear magnetic resonance (NMR)
J Sotelo and C M Slupsky, University of California, Davis, USA
- Introduction
- Experimental design and preparation
- Experimental process and analysis
- Current applications and future trends
- References
- Appendix: Abbreviations
Statistical methods in metabolomics
J R Stevens, Utah State University, USA
- Introduction
- Exploratory/visual approaches
- Inferential approaches
- Multiple hypothesis testing
- Ensemble learning approaches
- Conclusion
- References
- Appendix: Software packages used
Metabolic reconstruction databases and their application to metabolomics research
P D Karp, SRI International, USA
- Introduction
- Overview of Pathway/Genome Database (PGDB) construction
- Querying PGDBs
- Metabolomics applications
- Sources of further information and advice
- Conclusion
- Acknowledgements
- References
PART 2 APPLICATIONS OF METABOLOMICS IN HUMANS, PLANTS AND FOOD
Human samples for health assessments
P D Whitfield and M K Doherty, University of the Highlands and Islands, UK
- Introduction
- Sample collections and biobanks
- Variation in metabolite profiles of human biofluids and tissues
- Standards for metabolomic studies
- Conclusions and future trends
- References
Metabolomics in nutrition
S Moco, A Ross, F-P J Martin, S Collino, J-P Godin, S Rezzi and S Kochhar, Nestle Research Center, Switzerland
- Introduction
- Epidemiological studies and biomarkers of food intake
- Diet and metabolic syndrome
- The role of intestinal microbiota in nutrition
- Perspectives in nutrition research
- Future trends
- References
Current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications
L R Ruhaak and C B Lebrilla, University of California, Davis, USA
- Introduction
- Analysis of human milk oligosaccharides (HMOs)
- Applications of HMO analysis
- Conclusion
- References
- Appendix: Abbreviations
Metabolomic analysis of plants and crops
T Frank and K-H Engel, Technische Universität München, Germany
- Introduction
- Metabolomic studies on selected Poaceae species
- Metabolomic studies on selected Solanaceae species
- Metabolomic studies on selected Fabaceae species
- Metabolomic studies on selected Brassicaceae and Lamiaceae species
- Plant/crop metabolome databases
- Future trends
- References
Metabolomics for the safety assessment of genetically modified (GM) crops
D Stewart, The James Hutton Institute and Heriot-Watt University and L V T Shepherd, The James Hutton Institute, UK
- Introduction
- Solanaceous crops
- Cereal crops
- Other crops
- Metabolomics as part of a regulatory risk assessment procedure for the development and evaluation of genetically modified (GM) crops
- Metabolomics and GM food safety: future trends
- Acknowledgements
- References
Applications of metabolomics in food science: food composition and quality, sensory and nutritional attributes
E Chin and C M Slupsky, University of California Davis, USA
- Introduction
- Metabolomics for compound identification: authentication and pathogen detection
- Metabolomics for predicting sensory attributes
- Metabolomics and food processing and safety
- Conclusion
- References
- Appendix: Abbreviations