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Biomedical polymers

Edited by M Jenkins, University of Birmingham, UK

Woodhead Publishing Series in Biomaterials No. 7

...this publication offers an unsurpassable opportunity to facilitate immersion in a rapidly expanding interdisciplinary area.
Revista de Plásticos Modernos

...a source of reference for scientists and, in general, all professionals involved in the development and use of this important group of biomaterials.
Revista de Plásticos Modernos

 - reviews the latest research in this important group of biomaterials
 - discusses natural, synthetic, biodegradable and non-biodegradable polymers and their applications
 - examines the use of biomedical polymers in such areas as drug delivery systems and cell encapsulation
 - an essential reference for scientists and all those concerned with the development and use of this important group of biomaterials

Given the rapid development and use of biomaterials, it is becoming increasingly important to understand the structure, processing and properties of biomedical polymers and their medical applications. With its distinguished editor and team of international contributors, Biomedical Polymers reviews the latest research on this important group of biomaterials.

The book discusses natural, synthetic, biodegradable and non bio-degradable polymers and their applications. Chapters review polymeric scaffolds for tissue engineering and drug delivery systems, the use of polymers in cell encapsulation, their role as replacement materials for heart valves and arteries, and their applications in joint replacement. The book also discusses the use of polymers in biosensor applications.

Biomedical polymers is an essential reference for scientists and all those concerned with the development and use of this important group of biomaterials

ISBN 1 84569 070 2
ISBN-13: 978 1 84569 070 0
August 2007
236 pages  234 x 156mm  hardback  
£130.00 / US$220.00 / €155.00

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About the editor

Dr Mike Jenkins is a Senior Lecturer in the School of Engineering at the University of Birmingham, UK. Dr Jenkins has published widely in the field of polymers and is internationally renowned for his research in the area.

Titles which may also be of interest:
Natural-based polymers for biomedical applications
Medical textiles and biomaterials for healthcare
Medical and healthcare textiles
Medical modelling
Modelling degradation of bioresorbable polymeric medical devices

Contents

Introduction to polymeric scaffolds for tissue engineering
K Harrison
 - Introduction
 - Cells used in tissue engineering
 - The scaffold structure
 - Fabrication techniques for tissue scaffolds
 - Supercritical fluid processing (SCF)
 - Future trends
 - References

Introduction to polymeric drug delivery systems
K Harrison
 - Introduction: controlled drug release
 - Mechanisms of action for controlled drug release
 - Examples of controlled release delivery systems
 - Commonly used polymers for drug delivery systems
 - Polymer characteristics and properties
 - Future trends
 - References

Hydrogels in cell encapsulation and tissue engineering
A Hillel, P Shah and J Elisseeff, Johns Hopkins University, USA
 - Introduction
 - Structure and properties of a crosslinked hydrogel
 - Methods to form a hydrogel
 - Application to cell encapsulation and tissue engineering
 - Future Trends
 - Sources of further information and advice
 - References

Biodegradable polymers for drug delivery systems
G S Kwon and D F Ferguson, University of Wisconsin, USA
 - Introduction
 - Synthetic biodegradable block copolymers: polyanhydrides, poly(alkycyanoacrylates), polyphoshazenes and poly(phosphoesters)
 - Biodegradable polyesters for drug delivery
 - Poly(ethylenimine) (PEI) and polyethylene glycol-co-poly(L-lysine)-g-histidine (PEG-co-PLL-g-His)
 - Synthetic block copolypeptides
 - Future trends
 - References

Polymers as replacement materials for heart valves and arteries
D M Espino, University of Birmingham, UK
 - Introduction
 - The cardiovascular system
 - Replacing heart valves
 - Replacing arteries
 - Tissue engineered arteries
 - Summary and future trends
 - Sources of further information and advice
 - Acknowledgements
 - References

Ultra-high molecular weight polyethylene (UHMWPE) in joint replacement
F W Shen, University of California Los Angeles, USA
 - Introduction
 - The structure of UHMWPE
 - Fabrication of implants using UHMWPE
 - Implant sterilization
 - Crosslinking to improve implant wear properties
 - Future trends
 - Sources of further information and advice
 - References

Polymers in biosensors
F Davis and S P J Higson, Cranfield University, UK
 - Introduction
 - The development and format of biosensors
 - Polymer membranes in biosensors
 - Polymer coatings for biosensors
 - Conducting polymers in biosensors
 - Redox-active polymers in biosensors
 - Molecularly-imprinted polymers in biosensors
 - Summary and future trends
 - Sources of further information and advice
 - References

Tissue engineering using natural polymers
V M Correlo, M E Gomes, K Tuzlakoglu, J M Oliveira, P B Malafaya, J F Mano, N M Neves and R L Reis, University of Minho, Portugal
 - Introduction
 - Chitosan and starch-based polymers in tissue engineering
 - Production of 3D porous scaffolds by extrusion and injection moulding with a blowing agent
 - Producing 3D porous scaffolds using fibre bonding
 - Producing 3D porous scaffolds by melt based compression moulding with particulate leaching
 - 3D porous scaffolds produced by freeze-drying
 - Particle aggregation techniques to produce 3D porous scaffolds
 - Microwave processing of 3D polymeric scaffolds
 - Conclusions
 - References