This item is in: Biomedicine > Medical science and technology, cancer research

Human papillomavirus infections: From the laboratory to clinical practice

F Cobo, Hospital de Poniente, Spain

Woodhead Publishing Series in Biomedicine No. 14

This succinct review of the various facets of HPV invection and disease will be very useful for the intended audiences interested in this subject...There are no comparable books.
Doody's Reviews

 - covers all the important issues relating to both male and female HPV infection
 - provides overview of the current knowledge about epidemiology, basic virology, pathogenesis and diagnosis methods
 - explores the relationship between HPV and cancer
 - adds new information about treatment methods and prevention strategies

Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide, both in men and women. Human papillomavirus infections provides the scientific background needed to understand the natural history and pathogenesis of HPV infection and offers discussion of its clinical features, diagnosis, treatment and prevention. The book begins with chapters covering the epidemiology, virology, history and transmission of the infection, as well as its pathogenesis and clinical features. Following a discussion of the relationship between HPV and cancer, chapters in the second half of the book look at diagnosis, testing and treatment. The book concludes with detailed coverage of the prevention of HPV through worldwide vaccination programmes.

ISBN 1 907568 74 3
ISBN-13: 978 1 907568 74 9
July 2012
168 pages  234 x 156mm  hardback  
£99.00 / US$170.00 / €120.00

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About the author

Dr Fernando Cobo is a specialist in microbiology working in the Microbiology Department of the Hospital de Poniente, Spain, and has previously worked at the University Hospital Virgen de las Nievas and the Stem Cell Bank of Andalucía. He is a member of several professional societies including the Spanish Society of Infectious Diseases and Clinical Microbiology, and has published over 50 peer-reviewed journal articles, 10 books, 90 book chapters, and 120 national and international conference papers.

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Contents

Introduction and epidemiological data
 - Data about general epidemiology
 - HPV types and their relationship with human diseases
 - Epidemiology of HPV in men

Basic virology: structure and nomenclature
 - HPV nomenclature
 - HPV structure
 - Classification: types, subtypes and variants
 - Function of viral proteins

Natural history and transmission: anatomic distribution
 - Methods of transmission of HPV infections
 - Natural history of HPV infection

Pathogenesis and clinical features
 - Pathogenesis
 - Clinical features

HPV infection and association with cancer
 - The relationship between HPV and cancer

Diagnosis of HPV infection
 - Methods of specimen collection
 - Conventional and monolayer cytology
 - Histopathology
 - HPV nucleic acid detection
 - Serological assays
 - Diagnostic utility of P16INK4a
 - Evaluation of DNA testing and HPV mRNA with liquid-based cytology

Clinical utility of HPV testing
 - Screening programmes for cervical cancer diagnosis
 - Strategies for the management of HPV infection and risk of cancer

Treatment
 - Treatment of benign lesions
 - Treatment of precancerous lesions
 - Treatment of cancer

Prevention: HPV vaccines
 - HPV vaccine types
 - Recommendations for the use of HPV vaccines
 - HPV vaccine acceptance and licensure status
 - Areas for research in HPV vaccines
 - Therapeutic vaccines
 - The vaccination experience worldwide